MINNEAPOLIS (AP) — A federal agent shot and killed a Minneapolis motorist when she allegedly tried to run over law enforcement officers during an immigration crackdown in the city, authorities said Wednesday.

The Immigration and Customs Enforcement officer shot the woman in her vehicle in a residential neighborhood in Minneapolis, Department of Homeland Security spokeswoman Tricia McLaughlin said in a statement.

The shooting marks a dramatic escalation of the latest in a series of immigration enforcement operations in major American cities under the Trump administration.

The Twin Cities of Minneapolis and St. Paul have been on edge since DHS announced Tuesday that it had launched the operation, with 2,000 agents and officers expected to participate in the crackdown tied in part to allegations of fraud involving Somali residents.

A large throng of protesters gathered at the scene after Wednesday's shooting, where they vented their anger at the local and federal officers who were there, including Gregory Bovino, a senior U.S. Customs and Border Patrol official who has been the face of crackdowns in Los Angeles, Chicago and elsewhere.

In a scene similar to the Los Angeles and Chicago crackdowns, bystanders heckled the officers and blew whistles that have become ubiquitous during the crackdowns.

“Shame! Shame! Shame!” and “ICE out of Minnesota!” they loudly chanted from behind the police tape.

After the shooting, Mayor Jacob Frey said immigration agents were “causing chaos in our city.”

“We are demanding ICE leave the city and state immediately. We stand rock solid with our immigrant and refugee communities," Frey said on social media.

The area where the shooting occurred is a modest neighborhood south of downtown Minneapolis, just a few blocks from some of the oldest immigrant markets in the area and a mile (1.6 kilometers) from where George Floyd was killed by police in 2020.

The Immigration Defense Network, a coalition of groups serving immigrants in Minnesota, held a training session Tuesday night for about 100 people who are willing to hit the streets to monitor the federal enforcement.

“I feel like I'm an ordinary person, and I have the ability do something so I need to do it,” Mary Moran told KMSP-TV.

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Dell'Orto reported from St. Paul, Minnesota. Associated Press reporter Ed White in Detroit contributed.